{"id":8394,"date":"2020-01-15T12:11:40","date_gmt":"2020-01-15T09:11:40","guid":{"rendered":"http:\/\/prodiab.md\/?p=8394"},"modified":"2020-01-15T12:11:40","modified_gmt":"2020-01-15T09:11:40","slug":"o-proteina-noua-ar-putea-intarzia-aparitia-diabetului","status":"publish","type":"post","link":"http:\/\/prodiab.md\/ro\/o-proteina-noua-ar-putea-intarzia-aparitia-diabetului\/","title":{"rendered":"O protein\u0103 nou\u0103 ar putea \u00eent\u00e2rzia apari\u0163ia diabetului !"},"content":{"rendered":"

Diabetul de tip 1 a devenit o maladie pentru care eforturile oamenilor de \u015ftiin\u0163\u0103 se concentreaz\u0103 asupra \u0163inerii sub control \u015fi a prevenirii acesteia.<\/p>\n

Cercet\u0103torii de la Facultatea de Medicin\u0103 a Universit\u0103\u0163ii Indiana au f\u0103cut public\u0103 descoperirea unei proteine care \u00eempiedic\u0103 evolu\u0163ia acestui tip de diabet \u00een cazul oamenilor \u015fi care poate s\u0103 reprezinte un\u00a0 poten\u0163ial punct de plecare pentru terapii \u015fi tratamente.<\/p>\n

Cercet\u0103torii care au colaborat \u00een cadrul acestui studiu au plecat de la studierea celulelor beta, un subset al celulelor pancreatice care regleaz\u0103 r\u0103spunsul sistemului imunitar. Studiile anterioare au dovedit c\u0103 aceste celule joac\u0103 un rol important \u00een reglarea nivelului de zah\u0103r din s\u00e2ngele unei persoane \u015fi c\u0103, \u00een cazul unui subiect care sufer\u0103 de diabet de tipul 1, aceste celule sunt distruse de c\u0103tre sistemul imunitar.<\/p>\n

Scopul acestui studiu a fost acela de a identifica care sunt acele\u00a0proteine\u00a0care apar \u00een cazul diabetului \u015fi modul \u00een care acestea func\u0163ioneaz\u0103. \u00cen urma diferitelor exerimente, oamenii de \u015ftiin\u0163\u0103 au reu\u015fit s\u0103 identifice 11.324 proteine dintre care 387 au fost afectate de c\u0103tre tratamentele folosite \u00een cadrul studiului. Dintre toate aceste proteine, cercet\u0103torii \u015fi-au concentrat aten\u0163ia asupra uneia, factorul de diferen\u0163iere a cre\u015fterii 15 (GDF15), despre care se \u015ftie c\u0103 joac\u0103 un rol important \u00een protejarea diferitelor tipuri de celule umane. \u00cen cazul persoanelor cu diabet, la nivelul pancreasului, nivelul acestei proteine este \u00een sc\u0103dere.<\/p>\n

\u201eAm dorit s\u0103 identific\u0103m proteine care pot interveni \u00een procesul bolii diabetului\u201d, a declarat Ernesto Nakayasu, autor al studiului. \u201eAm fost interesa\u0163i de GDF15, deoarece nivelul proteinei a fost suprimat cu 70 la sut\u0103 dup\u0103 tratament\u201d, adaug\u0103 acesta.<\/p>\n

Observa\u0163iile realizate asupra proteinei GDF15 \u00een cazul \u015foriceilor deschid perspectiva unor noi forme de\u00a0tratament\u00a0dup\u0103 cum explic\u0103 dr. Raghu Mirmira: \u201eAceast\u0103 abordare difer\u0103 substan\u0163ial de g\u00e2ndirea actual\u0103 care vizeaz\u0103 sistemul imunitar. \u00cen timp ce GDF15 poate fi o nou\u0103 terapie, am identificat alte proteine care pot func\u0163iona \u00eempreun\u0103 cu GDF15, deci aceast\u0103 lucrare reprezint\u0103 \u00eentr-adev\u0103r un tezaur de informa\u0163ii care pot fi minate pentru noi terapii\u201d.<\/p>\n

Studiul a fost publicat \u00een\u00a0Cell Metabolism<\/em>.<\/p>\n

Sursa: www.\u00a0descopera.ro<\/p>","protected":false},"excerpt":{"rendered":"

Diabetul de tip 1 a devenit o maladie pentru care eforturile oamenilor de \u015ftiin\u0163\u0103 se concentreaz\u0103 asupra \u0163inerii sub control \u015fi a prevenirii acesteia. Cercet\u0103torii de la Facultatea de Medicin\u0103 a Universit\u0103\u0163ii Indiana au f\u0103cut public\u0103 descoperirea unei proteine care \u00eempiedic\u0103 evolu\u0163ia acestui tip de diabet \u00een cazul oamenilor \u015fi care poate s\u0103 reprezinte un\u00a0…<\/p>\n","protected":false},"author":3,"featured_media":8395,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"ngg_post_thumbnail":0},"categories":[5],"tags":[],"yoast_head":"\nO protein\u0103 nou\u0103 ar putea \u00eent\u00e2rzia apari\u0163ia diabetului ! - PRODIAB<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"http:\/\/prodiab.md\/ro\/o-proteina-noua-ar-putea-intarzia-aparitia-diabetului\/\" \/>\n<meta property=\"og:locale\" content=\"ro_RO\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"O protein\u0103 nou\u0103 ar putea \u00eent\u00e2rzia apari\u0163ia diabetului ! - PRODIAB\" \/>\n<meta property=\"og:description\" content=\"Diabetul de tip 1 a devenit o maladie pentru care eforturile oamenilor de \u015ftiin\u0163\u0103 se concentreaz\u0103 asupra \u0163inerii sub control \u015fi a prevenirii acesteia. 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